D. Alagille, R. Baldwin, G. Tamagnan
Feb 21, 2005
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0
Influential Citations
122
Citations
Quality indicators
Journal
Tetrahedron Letters
Abstract
Abstract We report the simple and efficient synthesis of 2-arylbenzothiazoles (‘BTA’) and 2-arylbenzoxazoles by direct coupling of benzothiazoles or benzoxazoles with aryl bromides. This method permits direct one-step access to precursors of radiolabeled BTA-1 and BTA-2 and their 6-methoxy analogues, used for in vivo imaging of β-amyloid plaques with positron emission tomography (PET).