Lin Yuan-bin
2007
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Journal
Chemical Reagents
Abstract
A new method for synthesizing 6-chloropyridine-3-carbaldehyde in one step is presented in this article.2-Chloro-5-(chloromethyl) pyridine was oxidized gently with sodium salt of 2-nitrpropane,which was formed from reaction of anhydrous alcohol,metallic sodium and 2-nitropropane to yield 6-chloropyridine-3-carbaldehyde.This method could harvest a high-purity product at a high yield.