Y. Guindon, B. Simoneaua, C. Yoakima
Sep 30, 1991
Citations
0
Influential Citations
11
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Acetals of dimethyl tartrate can be used to prepare optically active secondary alcohols from the corresponding aldehydes. The key step involves treatment of the acetals with dialkylboron bromides and higher order cuprates. The process involves an unusual mechanism and produces diastereoselectivities up to 82 : 1.