P. Bedos, L. Feliu, Jean Martínez
Jun 23, 2003
Citations
0
Influential Citations
2
Citations
Journal
Tetrahedron Letters
Abstract
Abstract We report the synthesis of 1,4,8-triazaspiro[4.5]decan-2-one derivatives from N -benzyl-4-piperidone and N -protected amino acid amides on solid support. We have translated the chemistry from solution to solid phase using a backbone amide linker (BAL) mimic. Using a parallel combinatorial approach, we performed the optimization of the synthesis on SynPhase™ Lanterns.