C. Heiss, M. Schlosser
Feb 1, 2003
Citations
0
Influential Citations
29
Citations
Journal
European Journal of Organic Chemistry
Abstract
In a case study, 1,2,3-trifluorobenzene was functionalized at each of the two vacant positions [producing the benzoic acids HO2CC6H2F3-2,3,4 F(I) and HO2CC6H2F3-3,4,5 (I)] and, in addn., bromine was introduced into all available positions of I and II. The required regioflexibility was achieved by applying novel organometallic recipes such as deprotonation-triggered halogen migrations and site-discriminating competitive halogen-metal permutations. [on SciFinder (R)]