Zheng Shao-cheng
2011
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Journal
Zhejiang Chemical Industry
Abstract
With the developments of molecular biology recently,chemistry and biochemistry,it is comfirmed that the compounds of glucose as prodrugs have good pharmacodynamics.Glucose pentaacetate is synthesized by complete acetylation.Because the acetyl is easyly removed,Glucose pentaacetate is generally used as intermediate of drug of derivatives of saccharide.The methods of synthesis and detectioin,peculiarity of physics and chemistry and applications of glucose pentaacetate are introduced.The main problems of synthesis technology are pointed out.The research directions to improve the yield are proposed.