G. G. Cross, Charles R. Eisnor, Robert A. Gossage
Mar 27, 2006
Citations
0
Influential Citations
14
Citations
Journal
Tetrahedron Letters
Abstract
Abstract An improved synthesis of the anti-cancer agent DMU-212 ( trans -3,4,5,4′-tetramethoxystilbene) is described. The methodology involves the use of a Pd-oxazoline catalyst as a mediator of a regio-selective (Heck) C–C bond formation reaction. A simple isolation step is then used to obtain the title material. The compound has been further characterised in the solid-state by X-ray diffraction methods.