G. John, P. Shannon
1978
Citations
0
Influential Citations
3
Citations
Journal
Journal of The Chemical Society-perkin Transactions 1
Abstract
Colupulone (2) when boiled under aerobic conditions in acid (pH 5.4) buffer is transformed in good yield to, amongst other products, two non-polar tricyclic ketones, 8-hydroxy-4,4-dimethyl-3-isopropyl-7-(3-methylbut-2-enyl)-9-(2-methylpropionyl)tricyclo[5,3,1,01,5]undecane-10,11-dione (12) and its didehydro-derivative (13), separable by silver nitrate–silicic acid chromatography. The minor product (13) may be obtained more conveniently by treatment of colupulone (2) with lead tetra-acetate.