Y. BerlinMichael, R. Aslanian, M. L. Ruiz
Aug 1, 2007
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Influential Citations
4
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Journal
Synthesis
Abstract
Oxidation of nitrogen-based methyl heteroaryls with molecular oxygen resulted in the formation of the corresponding benzyl alcohols. While experimentally easy and amenable to large-scale preparations, this approach has limitations with respect to the particular nature of heterocyclic substrates. Using this methodology, the title compound, 2-[ N-( TERT-butoxycarbonyl)amino]-4-pyri-dinecarbaldehyde, considered to be a versatile pharmaceutical intermediate, was prepared on a multigram scale.