P. Ács, Ernő Müller, Gábor Rangits
Dec 18, 2006
Citations
0
Influential Citations
31
Citations
Journal
Tetrahedron
Abstract
Abstract 2-Iodoaniline derivatives were used as bifunctional substrates in palladium-catalysed carbonylation. Depending on the substituents, two types of compounds were synthesised: having methyl or hydrogen in 4-position 2-aryl-benzo[ d ][1,3]oxazin-4-one derivatives have been formed, chloro, bromo, cyano or nitro groups in the same position resulted in the formation of dibenzo[ b , f ][1,5]-diazocine-6,12-dione derivatives. In the presence of various primary and secondary amines ( tert -butylamine, amino acid methyl esters) as N -nucleophiles 2-ketocarboxamides were obtained as major products in aminocarbonylation reaction with double carbon monoxide insertion.