M. Braun, P. Meletis, R. Visse
Dec 1, 2011
Citations
0
Influential Citations
9
Citations
Journal
Advanced Synthesis & Catalysis
Abstract
Doubly deprotonated carboxylic acids undergo smooth palladium-catalyzed carbon alkylations with the allylic substrates methyl allyl carbonate and (E)-methyl (pent-3-en-2-yl) carbonate to give γ,δ-unsaturated carboxylic acids. A diastereoselective and enantioselective protocol leads to (2S,3R)-hexenoic acid in 87% ee.