Tatsuo Ishiyama*, J. Takagi, Akihiro Kamon
Dec 7, 2003
Citations
0
Influential Citations
32
Citations
Journal
Journal of Organometallic Chemistry
Abstract
Abstract Cross-coupling reaction of bis(pinacolato)diboron with β-(trifluoromethanesulfonyloxy)-α,β-unsaturated carbonyl compounds was carried out in the presence of PdCl 2 (PPh 3 ) 2 –2PPh 3 (3 mol%) and KOPh in toluene or K 2 CO 3 in dioxane for the synthesis of cyclic and acyclic β-boryl-α,β-unsaturated esters, amides, and ketones in high yields. The vinylboronates thus obtained readily participated in carboncarbon bond formation such as cross-coupling with vinyl triflates and 1,4-addition to α,β-unsaturated ketones.