C. D. Campbell, Rebecca L. Greenaway, Oliver T. Holton
Apr 22, 2014
Citations
0
Influential Citations
21
Citations
Journal
Chemical communications
Abstract
Palladium-catalyzed cascade cyclization of bromoenynamides equipped with an additional alkyne or ynamide substituent affords azatricyclic products. Using 5- to 7-membered ring tethers, this chemistry offers a regiospecific route to highly-functionalized azacycles. Elaboration to the trikentrin B skeleton is achieved from the arylsilane cyclization products.