Li-Mei Wei, Li-Lan Wei, W. Pan
Jan 13, 2003
Citations
0
Influential Citations
11
Citations
Journal
Tetrahedron Letters
Abstract
Abstract The reaction of 1-alkynylcyclobutanols with aryl iodides in the presence of Pd(OAc) 2 and Et 3 N in acetonitrile at 80°C for 24 h gives 2-disubstituted methylenecyclopentan-1-ones in modest to good yields. The tandem insertion-ring expansion process proceeds via the formation of an alkynyl π-complex, followed by migration of a carbon-carbon bond of the tert -alkanol to form the cyclopentanones stereoselectively.