Ilaria Ambrogio, S. Cacchi*, G. Fabrizi
Apr 15, 2006
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0
Influential Citations
44
Citations
Journal
Organic letters
Abstract
[reaction: see text] The palladium-catalyzed reaction of ethyl 3-(o-trifluoroacetamidophenyl)-1-propargyl carbonate with piperazines in the presence of Pd(PPh(3))(4) in THF at 80 degrees C affords 2-(piperazin-1-ylmethyl)indoles in excellent yields. Good to excellent yields are also obtained with other secondary amines.