José C. Barcia, J. Cruces, J. Estévez
Jul 15, 2002
Citations
0
Influential Citations
22
Citations
Journal
Tetrahedron Letters
Abstract
Abstract We describe here a new, efficient general synthesis of o -acetylbenzoic acids by Heck palladium-catalyzed arylation of n -butyl vinyl ether with o -bromobenzoic acid esters and the use of these compounds as starting materials for the synthesis of 3-benzylideneisochroman-1,4-diones, which readily rearrange to 2-hydroxy-3-phenyl-1,4-naphthoquinones. The application of this strategy to the synthesis of indolo[2,3- b ]naphthalene-6,11-diones is also described.