Zengming Shen, Xiyan Lu
Nov 20, 2006
Citations
0
Influential Citations
56
Citations
Journal
Tetrahedron
Abstract
An efficient method for the synthesis of 2,3-disubstituted indoles with high selectivity from 2-ethynylaniline derivatives and α,β-unsaturated carbonyl compounds was developed. This Pd(II)-catalyzed reaction involves tandem intramolecular aminopalladation, olefin insertion and protonolysis of the carbon-palladium bond with the regeneration of Pd(II) species in the presence of halide ions.