C. Blackburn, B. Guan, P. Fleming
May 28, 1998
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0
Influential Citations
266
Citations
Quality indicators
Journal
Tetrahedron Letters
Abstract
Abstract A three-component condensation reaction between 2-aminopyridine, an aldehyde and an isonitrile catalyzed by scandium triflate affords derivatives of 3-aminoimidazo[1,2-a]pyridine; aminopyrazine reacts similarly. A library of heterocycles, prepared in high yield by parallel synthesis and purification on an ion-exchange resin, was subjected to further reactions at the amino group.