M. Menichincheri, D. F. Bassini, M. Gude
Jan 13, 2003
Citations
0
Influential Citations
8
Citations
Journal
Tetrahedron Letters
Abstract
Abstract In this Letter a fast and useful parallel synthesis approach to 4-amino-2,6-dialkylamino-pyridines is described starting from commercially available 2,6-difluoro-3,5-dichloro-pyridine. Both symmetrical and unsymmetrical derivatives have been synthesized respectively in two or three steps in good yields. The method described is mild, adaptable to combinatorial purposes and applicable to a variety of amines.