Yankun Hou, S. Higashiya, T. Fuchigami
Dec 12, 1997
Citations
0
Influential Citations
31
Citations
Journal
Journal of Organic Chemistry
Abstract
Highly regioselective monofluorination of 1-aryl-3-(phenylthio)oxindoles and 2-substituted-3-oxo-4-(phenylthio)-1,2,3,4-tetrahydroisoquinolines can be successfully carried out in the presence of Me4NF·4HF or Et4NF·3HF as a supporting electrolyte to provide the corresponding 3-fluorinated oxindole and 4-fluorinated isoquinoline derivatives in good yields. Carbon anodes as well as a platinum anode were found to be effective for the fluorination when Me4NF·4HF was used as the supporting electrolyte.