J. Geier, H. Lessmann, A. Rothe
Apr 1, 2003
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0
Influential Citations
3
Citations
Quality indicators
Journal
Contact Dermatitis
Abstract
While a list of allergens in protective rubber gloves was being compiled (1), a representative of a large European glove manufacturer indicated that the 2 dithiocarbamates currently tested in standard series and in rubber series, i.e. zinc diethyldithiocarbamate (ZDEC) and zinc dibutyldithiocarbamate (ZDBC), did not represent the full spectrum of dithiocarbamates currently used in glove production. Zinc dibenzyldithiocarbamate (ZBEC, CAS-No. 14726-36-4, Fig. 1) was said to be used as a vulcanizing agent even more frequently than ZDEC or ZDBC. Based on this information, ZBEC was patch tested in unselected, consecutive patients in addition to the standard series in 16 departments of dermatology, all members of the Information Network of Departments of Dermatology (IVDK; http://www.ivdk.org) and the German Contact Dermatitis Research Group (DKG). The objective of this study was to determine the frequency of sensitization to ZBEC and to investigate cross-reactions to other dithiocarbamates.