V. Batchu, V. Subramanian, K. Parasuraman
Oct 10, 2005
Citations
0
Influential Citations
48
Citations
Journal
Tetrahedron
Abstract
Abstract 2-Aminoethanol facilitated the alkynylation of aryl halides (Sonogashira reaction) under palladium/charcoal–copper catalysis in water affording a mild and practical method for the synthesis of arylalkynes. A variety of terminal alkynes were coupled with aryl iodides and bromides possessing no hydrophilic functional groups to give the coupled products in good to excellent yields.