R. E. Marsh, M. R. Narasimha Murthy, K. Venkatesan
Feb 16, 1977
Citations
0
Influential Citations
10
Citations
Journal
Journal of the American Chemical Society
Abstract
The crystal structures of tert-butyloxycarbonylglycyl-L-proline and its benzyl ester are respond. Both molecules show similar, extended conformation and there is no hint of the folded conformation that had earlier been suggested for tert-butyloxycarbonylglycyl-L-proline. It us shows that differences in the IR spectra of the two crystals, which had been interpreted in terms of an intramolecular hydrogen bond in the orthombic space group P2 1 2 1 2 1 , with cill dimensions a=5.743 (2), b=23.849 (5), and c=10.440 (2) A for the free peptide and a=15.381 (3), b=19.112 (4), c=6.638 (2) A for the benzyl ester. Least-squares refinement led to R indxes of 0.049 and 0.037 for 1344 and 2273 reflections with positive net intensity.