E. Atherton, Jill L. Holder, M. Meldal
1988
Citations
0
Influential Citations
49
Citations
Journal
Journal of The Chemical Society-perkin Transactions 1
Abstract
The preparation and characterisation of 3,4-dihydro-4-oxo-1,2,3-benzotriazinyl esters (1) of Fmoc-amino acids and their use in solid phase peptide synthesis is described. Ionisation of the liberated hydroxy component (2) by the starting resin-bound amine provides a useful colour indicator of the progress of acylation reactions.