E. Atherton, Linda R. Cameron, Robert C. Sheppard
1988
Citations
1
Influential Citations
87
Citations
Quality indicators
Journal
Tetrahedron
Abstract
Abstract The application of fluorenylmethoxycarbonyl-amino-acid pentafluorophenyl esters to solid phase peptide synthesis under polar reaction conditions is described. Reaction rates are increased in the presence of l-hydroxybenzotriazole. The technique is illustrated by preparation of decapeptide and dodecapeptide sequences.