Dirk Leifert, Denis G. Artiukhin, J. Neugebauer
Apr 21, 2016
Citations
0
Influential Citations
27
Citations
Journal
Chemical communications
Abstract
Arylisonitriles (2 equivalents) react with alkyl and perfluoroalkyl radicals to form 2-alkylated indole-3-imines via two sequential additions to the isonitrile moiety followed by homolytic aromatic substitution. The three component reaction comprises three C-C bond formations. The endocyclic imine functionality in the products is more reactive in follow up chemistry and hydrolysis of the exocyclic imine leads to 3-oxindoles that show fluorescence properties.