R. Garcia-Baquero, B. Madurga, M. García
Feb 1, 2013
Citations
0
Influential Citations
6
Citations
Quality indicators
Journal
Actas Urologicas Espanolas
Abstract
Abstract Objective To evaluate the effect of the treatment with fesoterodine fumarate in patients with overactive bladder, as an alternative in case of failure of the usual anticholinergic treatment, due to either lack of therapeutic efficacy or intolerance to side effects. Material and method A retrospective review of 158 patients with overactive bladder was carried out. The patients were divided into two groups: the first group consisting of 56 patients where the anticholinergic treatment was shown to be ineffective, and the second group; 102 patients who presented intolerance to anticholinergic side effects. Results For the first group where fesoterodine fumarate was used to improve effectiveness of the anticholinergics, improvement in the components of urinary urgency ( p = 0.001), insufficient emptying ( p = 0.001), incontinence ( p = 0.009), and in the number of pads/day ( p p p = 0.015) was seen, as well as a significant clinical improvement. Conclusion Fesoterodine fumarate is an optimal treatment option when the clinical response to anticholinergics has not been satisfactory, either by the lack of therapeutic action or by intolerance to side effects, and especially when the treatment is expected to be long.