M. Franceschin, A. Alvino, G. Ortaggi
Nov 29, 2004
Citations
1
Influential Citations
41
Citations
Journal
Tetrahedron Letters
Abstract
Several lipophilic perylene and coronene derivatives, employed mainly as liquid crystalline dyes are known and their synthesis has been widely studied. We have applied an analogue strategy using hydrophilic substituents to obtain highly water soluble perylene diimides (4) and a new hydrosoluble coronene derivative (CORON, 6), whose molecular features appear particularly suitable for inducing G-quadruplex DNA structures and inhibiting human telomerase.