J. Evenhuis, S. Ágoston, P. Salt
Jun 1, 1981
Citations
1
Influential Citations
46
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Quality indicators
Journal
British journal of anaesthesia
Abstract
The concentrations of 4-aminopyridine hydrochloride in the blood and urine from volunteers were measured following a bolus injection i.v. of 0.3 mg kg-1. The drug was assayed by means of a new GLC method which is described. The pharmacokinetics of 4-aminopyridine are complicated by an additional increase in plasma concentration during the elimination phase of the drug.