Y. Kumagai, T. Fujita, M. Ozaki
Feb 1, 2005
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Influential Citations
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Quality indicators
Journal
Clinical Pharmacology & Therapeutics
Abstract
Mosapride citrate is a selective 5‐HT4 receptor agonist which is used as a gastroprokinetic drug in Japan. It is expected that mosapride citrate alleviate gastrointestinal symptom in patients with postgastrectomy. However, solubility of the drug is decreased with increase of pH and in a dog model of distal partial gastrectomy, absorption of the drug is decreased. We studied pharmacokinetics of mosapride in patients operated by gastrectomy.