Welling Pg, Thomsen Jh, Shug Al
Feb 1, 1979
Citations
0
Influential Citations
15
Citations
Quality indicators
Journal
International journal of clinical pharmacology and biopharmacy
Abstract
: The pharmacokinetics of l-carnitine were studied in adult male patients following intravenous infusion of dl-carnitine hydrochloride-L-Carnitine appears to distribute into a rapidly perfused and then a more slowly perfused body space following administration. The overall apparent distribution volume Vd (ss) is consistent with extracellular body water. Serum levels of l-carnitine, from two different dose levels were adequately described by a two-compartment model. 80% of the administered dose was recovered in 24 hour post dose urine.