I. Tegeder, F. Neumann, F. Bremer
Jan 1, 1999
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Influential Citations
73
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Quality indicators
Journal
Clinical Pharmacology & Therapeutics
Abstract
Meropenem is a broad‐spectrum antibiotic used for severe infections. In patients with chronic end‐stage renal failure, meropenem clearance is reduced and doses must be adjusted according to the creatinine clearance. The aim of this study was to assess pharmacokinetic data of meropenem in patients with acute renal failure and to determine the amount of drug removed by continuous venovenous hemofiltration, an often‐used renal replacement therapy in patients with acute renal failure.