L. Na
2008
Citations
1
Influential Citations
2
Citations
Journal
Journal of Anhui Agricultural Sciences
Abstract
[Objective] The research aimed to provide theoretical basis for the reasonable application and environmental security of miloxacin used in Penaeus chinensis.[Method] Shrimps were kept in experimental tanks with aerated tapwater of 21-22 ℃.The shrimps were fed medicated feed by oral administration.The dosage of miloxacin(MLX) was 30 mg/kg body weight per day for 5 consecutive days.Study on pharmacokinetics of MLX in shrimp and distribution and elimination of MLX in mariculture environment of water and sediment was carried out by RP-HPLC.[Result] By 3P87,the elimination of MLX accorded with open two-compartment model.In the experiment,elimination of MLX was slow.Meanwhile,there was difference between the concentrations of surface and bottom,but the difference was not significant.The concentration-time curve of MLX in water was Y=-0.002 9ln X+0.008 6.[Conclusion] Sediment could adsorb miloxacin and miloxacin had the trend to shift into sediment.