Yoshihito Niki
2002
Citations
0
Influential Citations
15
Citations
Journal
Journal of Infection and Chemotherapy
Abstract
Tosufloxacin tosilate is a fluoroquinolone antibacterial agent developed by Toyama Chemical Co., Ltd. Phase I studies of tosufloxacin tosilate were conducted in 1986, followed by double-blind, comparative studies from 1987 through 1988. Tosufloxacin tosilate was approved for the indications of respiratory infections, urinary tract infections, hepatobiliary infections, and gastrointestinal infections, and was launched in 1990. Subsequently, additional indications were approved for Chlamydia trachomatis, urethritis non gonorrphoica, infectious diseases in the field of plastic surgery, typhoid fever, and paratyphoid fever. Twelve years have passed since the launch of tosufloxacin tosilate and it has won the confidence of physicians. In this article, the pharmacokinetics and safety assessments of tosufloxacin tosilate are described.