O. Seitz
May 28, 1999
Citations
0
Influential Citations
9
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Boc/Z-protected PNA oligomers were synthesised on solid phase. The use of the allylic HYCRON resin allowed for the application of both Boc- and Fmoc-protecting groups. Highest yields were obtained when the monomeric building block was synthesised on solid phase rather than loaded as preformed unit. The selective attachment of fluorescent labels at the C-terminal (3′) end demonstrated for the first time that further manipulations on protected PNA fragments are feasible.