P. Pierrat, P. Gros, Y. Fort
Aug 18, 2005
Citations
1
Influential Citations
38
Citations
Journal
Journal of combinatorial chemistry
Abstract
2-Chloro-5-bromopyridine was immobilized on polystyrene via selective introduction of a traceless silicon linker at the C-4 position. A useful scaffold was thus obtained, as demonstrated by efficient and selective reactions with polar and transition organometallic reagents, opening a new access to pyridine-based libraries of synthons and chromophores.