A. Dubnika, K. Veldre, A. Actiņš
Apr 28, 2011
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Abstract
Ipidacrine hydrochloride is pharmaceutically active compound that forms variety of crystalline modifications which differs by solvent type and content in crystalline structure. These crystalline forms analyzed by powder x-ray diffraction, differential thermal analysis, thermogravimetry and Karl Fisher titration. Obtained crystalline forms include two monohydrates, two hemihydrates, two anhydrous forms, two non-stoichiometric hydrates and mixed solvates with octanol and water and methanol and water, solvate with chloroform and dimethylformamide.