J. Bauman, J. Harrison, E. Arnold
Jan 1, 2016
Citations
1
Influential Citations
21
Citations
Journal
IUCrJ
Abstract
4-Bromopyrazole and 4-iodopyrazole bind to many small molecule binding hot spots in target proteins. This promiscuous binding enables the use of these compounds for experimental phase determination by single-wavelength anomalous dispersion (SAD). The low cost and safety of the compounds make them excellent choices for addition to the protein crystallographer’s toolkit.