E. Bering
Nov 1, 1956
Citations
0
Influential Citations
11
Citations
Journal
Journal of neurosurgery
Abstract
T UE use of phenolsulphonphthalein to study the cerebrospinal fluid system was introduced by Dandy and Blackfan in 1913. 4,5 They assumed this dye labeled cerebrospinal fluid as a whole and that it could be used as a measure of the absorption rate of cerebrospinal fluid as well as communication between the ventricles and the spinal subarachnoid space. However, new information about the cerebrospinal fluid which has been obtained through the use of radio-active and stable isotope tracers ~-a has made it necessary to re-examine the basic principles involved in this test to determine whether or not the interpretations usually placed on it are valid. This paper is a study of this test based upon some 301 dye studies done on various patients of the neurosurgical service of The Children's Medical Center, Boston.