K. Kudryavtsev, Polina M Ivantcova, A. Churakov
Aug 15, 2012
Citations
0
Influential Citations
10
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Phenyl α-bromovinyl sulfone reacts with glycine ester Schiff bases regioselectively in the presence of catalytic amounts of AgOAc and DBU yielding polysubstituted pyrrolidine cycloadducts. Utilization of excess DBU induces subsequent facile aromatization of the cycloadducts and affords 5-arylpyrrole-2-carboxylic acid esters in 39–85% yields in a single step.