Lan-lan Xu, Can-Can Zhang, Xin-Yue Zhu
Aug 1, 2017
Citations
0
Influential Citations
20
Citations
Journal
Natural Product Research
Abstract
Abstract A new phenyl ether derivative, 3-hydroxy-5-(3-hydroxy-5-methylphenoxy)-4-methoxybenzoic acid (1), along with two known analogues, 3,4-dihydroxy-5-(3-hydroxy-5-methylphenoxy)benzoic acid (2) and 3-hydroxy-5-(3-hydroxy-5-methylphenoxy)benzoic acid (3), were isolated from the fungus Aspergillus carneus collected from South China Sea. The structure elucidation of 1 was determined based on extensive NMR and MS spectroscopic analyses. Compound 2 showed a strong antioxidant activity with an IC50 value of 19.3 μM which was close to the positive control ascorbic acid (IC50 = 15.3 μM).