A. Arduini, J. Dejulia, V. Damonti
1989
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Abstract
Phenylhydrazine (PH) represents an interesting probe in oxidative damage studies in human erythrocytes. We have recently demonstrated that spectrin, one of the most important cytoskeleton membrane proteins, was degraded after exposure of human red blood cells to PH. Because spectrin seems to be involved in the maintenance of phase-state asymmetry in the erythrocyte membrane, we decided to study the membrane phospholipid organization (MPO) in PH treated human red cells utilizing different methodological approaches.