R. Fan, F. Wen, Luoheng Qin
Oct 15, 2007
Citations
0
Influential Citations
36
Citations
Journal
Tetrahedron Letters
Abstract
Abstract (Diacetoxyiodo)benzene (PhI(OAc) 2 ) was found to be a powerful reagent to induce the intramolecular oxidative bromocyclization of homoallylic sulfonamides utilizing KBr as the bromine source. The reaction affords 2-substituted-4-bromo-pyrrolidines in moderate to excellent yields under a mild metal-free condition, and offers good manipulability by avoiding the use of highly toxic and caustic bromine (Br 2 ).