M. Ueki, Jun Tachibana, Yusuke Ishii
Jul 8, 1996
Citations
0
Influential Citations
9
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Z-Tyr[P(O)(NHR) 2 ]-OBzl (R= n -Pr and i -Pr) were obtained by reactions of Z-Tyr-OBzl, lithiated with LDA, with N , N ′-dipropyl- or diisopropyl-phosphorodiamidic chloride. Fmoc derivatives, Fmoc-Tyr[P(O)(NHR) 2 ]-OH, were obtained from them as stable crystals. The PN bonds are stable toward 20% piperidine in DMF and were cleaved completely with 95% trifluoroacetic acid.