Xiao‐Nan Zhang, M. Shi
Feb 21, 2013
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0
Influential Citations
67
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Journal
ACS Catalysis
Abstract
4,4-Dicyano-2-methylenebut-3-enoates are employed in the phosphine-catalyzed [3 + 2] cycloaddition with allenoates for the first time, affording regiospecific [3 + 2]-annulation products in moderate to good yields. The multifunctional chiral thiourea-phosphines having an axially chiral binaphthyl scaffold are effective catalysts for the asymmetric variant of this reaction, giving the α-regioisomers in good yields and moderate enantioselectivities.