T. Shioiri*, Y. Yokoyama, Y. Kasai
1976
Citations
0
Influential Citations
103
Citations
Quality indicators
Journal
Tetrahedron
Abstract
Abstract Diethyl phosphorocyanidate(DEPC) reacts with carboxylic acids in the presence of triethylamine leading to transient formation of acyl cyanides, but in presence of alcohols or amines, carboxylic esters or amides are produced. DEPC is especially effective for the synthesis of amides and peptides, and showed a satisfactory result on the Young racemization test.