L. A. Cates, R. L. Gallio, M. Cramer
Oct 1, 1973
Citations
0
Influential Citations
4
Citations
Quality indicators
Journal
Journal of pharmaceutical sciences
Abstract
N-1-Adamantylphosphoramidic dichloride and the dimethyl and diphenyl esters of the corresponding acid were synthesized and evaluated for biological activity. The dimethyl ester delayed the onset of tremorine-induced tremors and reduced locomotor activity, while the diphenyl derivative slightly antagonized perphenazine-induced catatonic reactions. None of the agents displayed activity against lymphoid leukemia.