B. Liorber, T. A. Tarzivolova, I. V. Zaikonnikova
May 1, 1986
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Journal
Pharmaceutical Chemistry Journal
Abstract
Diphenylphosphinyl acetohydrazide (I), which possesses neurotropic activity, has been recommended for the treatment of a number of nervous conditions [i]. The molecule of I contains the hydrazide moiety, and it may therefore be assumed to dissociate in solution, however, examination of the acid--base equilibrium of the drug showed it to be present in the molecular form over the pH range 3.0-10.0 [4].