Hugo Gattuso, A. Monari, M. Marazzi
Feb 7, 2017
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0
Influential Citations
30
Citations
Journal
RSC Advances
Abstract
We present the study of optical and photophysical properties of chlorin e6, a known photosensitizer producing singlet oxygen. The linear and non-linear optical properties have been studied taking into account the dynamical and vibrational effects both by using Wigner distribution or coupling with molecular dynamics. A force field correctly describing the out-of-plane vibrations has been properly parameterized. The photophysical study revealed a possible efficient population of the triplet manifold, from the S1 minimum region. Hence, fluorescence and singlet oxygen production are shown to coexist. Two-photon absorption high cross-section and far infrared absorption also suggest the possible use of chlorin e6 as an efficient sensitizer in two-photon absorption based phototherapy.