Sarit S. Agasti, A. Chompoosor, C. You
Apr 7, 2009
Citations
3
Influential Citations
389
Citations
Quality indicators
Journal
Journal of the American Chemical Society
Abstract
An anticancer drug (5-fluorouracil) was conjugated to the surface of gold nanoparticles through a photocleavable o-nitrobenzyl linkage. In this system, the particle serves as both cage and carrier for the therapeutic, providing a nontoxic conjugate that effectively releases the payload upon long wavelength UV irradiation.